The effect of gold nanoparticle capping agents on 1O2 detection by singlet oxygen sensor green

Singlet Oxygen Sensor Green (SOSG) is the most widely used fluorescent probe for detecting singlet oxygen (1O2). 1O2 can be efficiently produced by exciting surface plasmon of gold nanoparticles with laser pulses. However, are usually embedded in a chemical stabilizer that interact SOSG, leading to erroneous detection 1O2. This article shows emission properties SOSG strongly depend on concentration cetyltrimethylammonium bromide (CTAB), capping agent synthesis and stabilization. The sensitivity also drastically affected presence CTAB. effect due probe's aggregation CTAB premicellar aggregates micelles, emergence conformers micelles. Furthermore, behavior two other widely-used agents, i.e., citrate Polyethylene Glycol (PEG), investigated determine right nanoparticle use probe.